{"id":5625,"date":"2025-03-31T23:31:23","date_gmt":"2025-03-31T15:31:23","guid":{"rendered":"https:\/\/www.51mdea.com\/5625.html"},"modified":"2025-03-31T23:31:23","modified_gmt":"2025-03-31T15:31:23","slug":"%e6%8e%a2%e7%b4%a2n-%e7%94%b2%e5%9f%ba%e5%92%aa%e5%94%91%ef%bc%88cas-616-47-7%ef%bc%89%e7%9a%84%e5%90%88%e6%88%90%e5%b7%a5%e8%89%ba%ef%bc%9a%e6%8a%80%e6%9c%af%e5%88%9b%e6%96%b0%e4%b8%8e%e6%88%90","status":"publish","type":"post","link":"https:\/\/www.51mdea.com\/5625.html","title":{"rendered":"\u63a2\u7d22N-\u7532\u57fa\u54aa\u5511\uff08CAS 616-47-7\uff09\u7684\u5408\u6210\u5de5\u827a\uff1a\u6280\u672f\u521b\u65b0\u4e0e\u6210\u672c\u63a7\u5236"},"content":{"rendered":"

N-\u7532\u57fa\u54aa\u5511\uff1a\u4ece\u5b9e\u9a8c\u5ba4\u5230\u5de5\u4e1a\u7684\u5947\u5999\u65c5\u7a0b<\/h1>\n
\u5728\u5316\u5b66\u4e16\u754c\u91cc\uff0c\u6709\u8fd9\u6837\u4e00\u7c7b\u5206\u5b50\uff0c\u5b83\u4eec\u5c31\u50cf\u9690\u85cf\u5728\u89d2\u843d\u91cc\u7684\u9b54\u672f\u5e08\uff0c\u770b\u4f3c\u4e0d\u8d77\u773c\uff0c\u5374\u80fd\u6084\u65e0\u58f0\u606f\u5730\u6539\u53d8\u6211\u4eec\u7684\u751f\u6d3b\u3002N-\u7532\u57fa\u54aa\u5511\uff08N-Methylimidazole, \u7b80\u79f0NMI\uff09\uff0c\u5c31\u662f\u8fd9\u6837\u4e00\u4e2a\u4f4e\u8c03\u5374\u53c8\u4e0d\u53ef\u6216\u7f3a\u7684\u5b58\u5728\u3002\u4f5c\u4e3a\u54aa\u5511\u7c7b\u5316\u5408\u7269\u5bb6\u65cf\u4e2d\u7684\u4e00\u5458\uff0c\u5b83\u4e0d\u4ec5\u62e5\u6709\u8ff7\u4eba\u7684\u5316\u5b66\u7ed3\u6784\uff0c\u8fd8\u5728\u4f17\u591a\u9886\u57df\u5c55\u73b0\u51fa\u975e\u51e1\u7684\u5e94\u7528\u6f5c\u529b\u3002\u4ece\u7cbe\u7ec6\u5316\u5de5\u5230\u533b\u836f\u4e2d\u95f4\u4f53\uff0c\u4ece\u50ac\u5316\u5242\u5230\u79bb\u5b50\u6db2\u4f53\uff0cN-\u7532\u57fa\u54aa\u5511\u7684\u8eab\u5f71\u65e0\u5904\u4e0d\u5728\u3002<\/p>\n
\u7136\u800c\uff0c\u8fd9\u4f4d\u201c\u5e55\u540e\u82f1\u96c4\u201d\u7684\u8bde\u751f\u5e76\u975e\u4e00\u5e06\u98ce\u987a\u3002\u4f5c\u4e3a\u4e00\u79cd\u91cd\u8981\u7684\u6709\u673a\u5408\u6210\u539f\u6599\uff0cN-\u7532\u57fa\u54aa\u5511\u7684\u5236\u5907\u5de5\u827a\u7ecf\u5386\u4e86\u6f2b\u957f\u800c\u590d\u6742\u7684\u63a2\u7d22\u8fc7\u7a0b\u3002\u79d1\u5b66\u5bb6\u4eec\u4e3a\u4e86\u627e\u5230\u66f4\u9ad8\u6548\u3001\u66f4\u73af\u4fdd\u7684\u5408\u6210\u65b9\u6cd5\uff0c\u4ed8\u51fa\u4e86\u65e0\u6570\u5fc3\u8840\u3002\u672c\u6587\u5c06\u5e26\u9886\u8bfb\u8005\u6df1\u5165\u4e86\u89e3N-\u7532\u57fa\u54aa\u5511\u7684\u5408\u6210\u5de5\u827a\uff0c\u63a2\u8ba8\u6280\u672f\u521b\u65b0\u5982\u4f55\u63a8\u52a8\u5176\u751f\u4ea7\u6210\u672c\u7684\u964d\u4f4e\uff0c\u540c\u65f6\u5206\u6790\u8fd9\u4e00\u8fc7\u7a0b\u4e2d\u6240\u9762\u4e34\u7684\u6311\u6218\u4e0e\u673a\u9047\u3002<\/p>\n

\u4ec0\u4e48\u662fN-\u7532\u57fa\u54aa\u5511\uff1f<\/h2>\n

\u5316\u5b66\u6027\u8d28\u4e0e\u7ed3\u6784<\/h3>\n
N-\u7532\u57fa\u54aa\u5511\u662f\u4e00\u79cd\u542b\u6709\u54aa\u5511\u73af\u7684\u6709\u673a\u5316\u5408\u7269\uff0c\u5316\u5b66\u5f0f\u4e3aC4H6N2\u3002\u5b83\u7684\u5206\u5b50\u91cf\u4ec5\u4e3a82.10 g\/mol\uff0c\u5374\u8574\u542b\u7740\u4e30\u5bcc\u7684\u5316\u5b66\u6d3b\u6027\u3002\u54aa\u5511\u73af\u4e0a\u7684\u6c2e\u539f\u5b50\u8d4b\u4e88\u4e86\u5b83\u78b1\u6027\u7279\u6027\uff0c\u4f7f\u5176\u80fd\u591f\u53c2\u4e0e\u591a\u79cd\u4eb2\u6838\u53cd\u5e94\u548c\u9178\u78b1\u50ac\u5316\u8fc7\u7a0b\u3002\u6b64\u5916\uff0c\u7531\u4e8eN-\u7532\u57fa\u54aa\u5511\u5177\u6709\u8f83\u9ad8\u7684\u6cb8\u70b9\uff08\u7ea6229\u00b0C\uff09\u548c\u826f\u597d\u7684\u6eb6\u89e3\u6027\uff0c\u5b83\u5728\u5b9e\u9645\u5e94\u7528\u4e2d\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u7a33\u5b9a\u6027\u3002<\/p>\n

\u5e94\u7528\u9886\u57df<\/h3>\n
N-\u7532\u57fa\u54aa\u5511\u5e7f\u6cdb\u5e94\u7528\u4e8e\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\uff1a<\/p>\n
\n
\u533b\u836f\u884c\u4e1a<\/strong>\uff1a\u4f5c\u4e3a\u6297\u771f\u83cc\u836f\u7269\u7684\u91cd\u8981\u4e2d\u95f4\u4f53\uff1b<\/li>\n
\u5316\u5de5\u9886\u57df<\/strong>\uff1a\u7528\u4e8e\u5236\u5907\u9ad8\u6027\u80fd\u805a\u5408\u7269\u548c\u529f\u80fd\u6027\u6750\u6599\uff1b<\/li>\n
\u80fd\u6e90\u5b58\u50a8<\/strong>\uff1a\u4f5c\u4e3a\u79bb\u5b50\u6db2\u4f53\u7684\u6838\u5fc3\u7ec4\u5206\u4e4b\u4e00\uff0c\u63d0\u5347\u7535\u6c60\u6027\u80fd\uff1b<\/li>\n
\u50ac\u5316\u5242<\/strong>\uff1a\u56e0\u5176\u72ec\u7279\u7684\u7535\u5b50\u5206\u5e03\uff0c\u6210\u4e3a\u8bb8\u591a\u6709\u673a\u53cd\u5e94\u4e2d\u7684\u5173\u952e\u52a9\u5242\u3002<\/li>\n<\/ul>\n
\u53ef\u4ee5\u8bf4\uff0cN-\u7532\u57fa\u54aa\u5511\u4e0d\u4ec5\u662f\u79d1\u5b66\u7814\u7a76\u4e2d\u7684\u660e\u661f\u5206\u5b50\uff0c\u66f4\u662f\u73b0\u4ee3\u5de5\u4e1a\u4f53\u7cfb\u4e2d\u4e0d\u53ef\u6216\u7f3a\u7684\u4e00\u73af\u3002<\/p>\n
\n
\u5408\u6210\u5de5\u827a\u6982\u8ff0<\/h1>\n
\u65e2\u7136N-\u7532\u57fa\u54aa\u5511\u5982\u6b64\u91cd\u8981\uff0c\u90a3\u4e48\u5b83\u662f\u5982\u4f55\u88ab\u5236\u9020\u51fa\u6765\u7684\u5462\uff1f\u63a5\u4e0b\u6765\uff0c\u6211\u4eec\u5c06\u8be6\u7ec6\u5256\u6790\u51e0\u79cd\u4e3b\u6d41\u7684\u5408\u6210\u65b9\u6cd5\uff0c\u5e76\u7ed3\u5408\u56fd\u5185\u5916\u6587\u732e\u8d44\u6599\uff0c\u63ed\u793a\u6bcf\u79cd\u6280\u672f\u7684\u7279\u70b9\u53ca\u5176\u4f18\u52a3\u3002<\/p>\n
\u65b9\u6cd5\u4e00\uff1a\u7532\u57fa\u5316\u6cd5<\/h2>\n
\u539f\u7406\u7b80\u4ecb<\/h3>\n
\u7532\u57fa\u5316\u6cd5\u662f\u76ee\u524d\u5de5\u4e1a\u4e0a\u5e38\u7528\u7684N-\u7532\u57fa\u54aa\u5511\u5408\u6210\u8def\u7ebf\u4e4b\u4e00\u3002\u8be5\u65b9\u6cd5\u4ee5\u54aa\u5511\u4e3a\u8d77\u59cb\u539f\u6599\uff0c\u901a\u8fc7\u4e0e\u7532\u57fa\u5316\u8bd5\u5242\u53d1\u751f\u53d6\u4ee3\u53cd\u5e94\u751f\u6210\u76ee\u6807\u4ea7\u7269\u3002\u5e38\u89c1\u7684\u7532\u57fa\u5316\u8bd5\u5242\u5305\u62ec\u786b\u9178\u4e8c\u7532\u916f\uff08DMS\uff09\u3001\u6c2f\u7532\u70f7\uff08CH3Cl\uff09\u4ee5\u53ca\u7898\u7532\u70f7\uff08CH3I\uff09\u7b49\u3002<\/p>\n
\u53cd\u5e94\u65b9\u7a0b\u5f0f<\/h4>\n
$$
\ntext{Imidazole} + text{CH}_3text{X} xrightarrow{text{Catalyst}} text{N-Methylimidazole} + text{HX}
\n$$<\/p>\n
\u5176\u4e2d\uff0c$text{X}$\u4ee3\u8868\u5364\u7d20\u6216\u78fa\u9178\u57fa\u56e2\u3002<\/p>\n
\u5de5\u827a\u7279\u70b9<\/h3>\n
\n
\n
\u4f18\u70b9<\/strong> <\/p>\n
\n
\u64cd\u4f5c\u7b80\u5355\uff0c\u6613\u4e8e\u5b9e\u73b0\u89c4\u6a21\u5316\u751f\u4ea7\uff1b <\/li>\n
\u4ea7\u54c1\u7eaf\u5ea6\u9ad8\uff0c\u9002\u5408\u5bf9\u8d28\u91cf\u8981\u6c42\u4e25\u683c\u7684\u573a\u666f\u3002<\/li>\n<\/ul>\n<\/li>\n
\n
\u7f3a\u70b9<\/strong> <\/p>\n
\n
\u4f7f\u7528\u67d0\u4e9b\u7532\u57fa\u5316\u8bd5\u5242\uff08\u5982DMS\uff09\u5b58\u5728\u6bd2\u6027\u95ee\u9898\uff0c\u9700\u4e25\u683c\u63a7\u5236\u64cd\u4f5c\u6761\u4ef6\uff1b <\/li>\n
\u526f\u4ea7\u7269\u8f83\u591a\uff0c\u53ef\u80fd\u589e\u52a0\u540e\u7eed\u5206\u79bb\u63d0\u7eaf\u7684\u96be\u5ea6\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n
\u56fd\u5185\u5916\u7814\u7a76\u73b0\u72b6<\/h3>\n
\u6839\u636e\u4e2d\u56fd\u79d1\u5b66\u9662\u67d0\u7814\u7a76\u6240\u53d1\u8868\u7684\u4e00\u7bc7\u8bba\u6587\u663e\u793a\uff0c\u8fd1\u5e74\u6765\uff0c\u79d1\u7814\u4eba\u5458\u5c1d\u8bd5\u5f00\u53d1\u7eff\u8272\u5316\u7684\u7532\u57fa\u5316\u5de5\u827a\uff0c\u4f8b\u5982\u91c7\u7528\u76f8\u8f6c\u79fb\u50ac\u5316\u5242\uff08PTC\uff09\u6765\u63d0\u9ad8\u53cd\u5e94\u6548\u7387\u5e76\u51cf\u5c11\u73af\u5883\u6c61\u67d3\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u56fd\u5916\u5b66\u8005\u4e5f\u63d0\u51fa\u4e86\u4e00\u79cd\u57fa\u4e8e\u5fae\u901a\u9053\u53cd\u5e94\u5668\u7684\u6280\u672f\u65b9\u6848\uff0c\u8fdb\u4e00\u6b65\u7f29\u77ed\u4e86\u53cd\u5e94\u65f6\u95f4\uff0c\u964d\u4f4e\u4e86\u80fd\u8017\u3002<\/p>\n\n\n\n\n\n\n\n
\u53c2\u6570<\/th>\n \u4f20\u7edf\u65b9\u6cd5<\/th>\n \u6539\u8fdb\u540e\u65b9\u6cd5<\/th>\n<\/tr>\n<\/thead>\n
\u8f6c\u5316\u7387<\/td>\n 75%-80%<\/td>\n >90%<\/td>\n<\/tr>\n
\u53cd\u5e94\u65f6\u95f4<\/td>\n 6-8\u5c0f\u65f6<\/td>\n 1-2\u5c0f\u65f6<\/td>\n<\/tr>\n
\u50ac\u5316\u5242\u7528\u91cf<\/td>\n \u9ad8<\/td>\n \u4f4e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\u65b9\u6cd5\u4e8c\uff1a\u52a0\u6c22\u80fa\u5316\u6cd5<\/h2>\n
\u539f\u7406\u7b80\u4ecb<\/h3>\n
\u52a0\u6c22\u80fa\u5316\u6cd5\u662f\u4e00\u79cd\u76f8\u5bf9\u8f83\u65b0\u7684\u5408\u6210\u8def\u5f84\uff0c\u4e3b\u8981\u5229\u7528\u4e59\u7094\u548c\u6c28\u6c14\u4f5c\u4e3a\u521d\u59cb\u539f\u6599\uff0c\u5728\u7279\u5b9a\u6761\u4ef6\u4e0b\u751f\u6210\u54aa\u5511\u73af\uff0c\u968f\u540e\u518d\u5f15\u5165\u7532\u57fa\u57fa\u56e2\u5b8c\u6210\u7ec8\u8f6c\u5316\u3002<\/p>\n
\u53cd\u5e94\u6b65\u9aa4<\/h4>\n
\n
$text{HC} equiv text{CH} + 2text{NH}_3 xrightarrow{text{Ni Catalyst}} text{Imidazole}$ <\/li>\n
$text{Imidazole} + text{CH}_3text{X} to text{N-Methylimidazole}$<\/li>\n<\/ol>\n
\u5de5\u827a\u7279\u70b9<\/h3>\n
\n
\n
\u4f18\u70b9<\/strong> <\/p>\n
\n
\u539f\u6599\u6765\u6e90\u5e7f\u6cdb\uff0c\u4ef7\u683c\u4f4e\u5ec9\uff1b <\/li>\n
\u7406\u8bba\u4e0a\u53ef\u4ee5\u5b9e\u73b0\u96f6\u6392\u653e\uff0c\u7b26\u5408\u53ef\u6301\u7eed\u53d1\u5c55\u7406\u5ff5\u3002<\/li>\n<\/ul>\n<\/li>\n
\n
\u7f3a\u70b9<\/strong> <\/p>\n
\n
\u5bf9\u8bbe\u5907\u8981\u6c42\u8f83\u9ad8\uff0c\u5c24\u5176\u662f\u9ad8\u538b\u53cd\u5e94\u91dc\u7684\u8bbe\u8ba1\uff1b <\/li>\n
\u53cd\u5e94\u6761\u4ef6\u82db\u523b\uff0c\u9700\u8981\u7cbe\u786e\u8c03\u63a7\u6e29\u5ea6\u548c\u538b\u529b\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n
\u56fd\u5185\u5916\u7814\u7a76\u73b0\u72b6<\/h3>\n
\u5fb7\u56fd\u67d0\u5927\u5b66\u7684\u7814\u7a76\u56e2\u961f\u66fe\u9488\u5bf9\u52a0\u6c22\u80fa\u5316\u6cd5\u8fdb\u884c\u7cfb\u7edf\u4f18\u5316\uff0c\u53d1\u73b0\u901a\u8fc7\u8c03\u6574\u954d\u50ac\u5316\u5242\u7684\u8d1f\u8f7d\u91cf\uff0c\u53ef\u663e\u8457\u63d0\u5347\u54aa\u5511\u7684\u4ea7\u7387\u3002\u800c\u5728\u56fd\u5185\uff0c\u6e05\u534e\u5927\u5b66\u7684\u4e00\u9879\u4e13\u5229\u5219\u63d0\u51fa\u4e86\u4f7f\u7528\u6539\u6027\u91d1\u5c5e\u6c27\u5316\u7269\u50ac\u5316\u5242\u7684\u65b0\u601d\u8def\uff0c\u6210\u529f\u5c06\u53cd\u5e94\u6e29\u5ea6\u964d\u4f4e\u4e86\u8fd150\u00b0C\u3002<\/p>\n\n\n\n\n\n\n\n
\u53c2\u6570<\/th>\n \u521d\u59cb\u65b9\u6848<\/th>\n \u4f18\u5316\u540e\u65b9\u6848<\/th>\n<\/tr>\n<\/thead>\n
\u6e29\u5ea6<\/td>\n 300\u00b0C<\/td>\n 250\u00b0C<\/td>\n<\/tr>\n
\u538b\u529b<\/td>\n 10 MPa<\/td>\n 8 MPa<\/td>\n<\/tr>\n
\u9009\u62e9\u6027<\/td>\n 85%<\/td>\n >95%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\u65b9\u6cd5\u4e09\uff1a\u751f\u7269\u9176\u50ac\u5316\u6cd5<\/h2>\n
\u539f\u7406\u7b80\u4ecb<\/h3>\n
\u751f\u7269\u9176\u50ac\u5316\u6cd5\u662f\u4e00\u79cd\u5b8c\u5168\u4e0d\u540c\u4e8e\u4f20\u7edf\u5316\u5b66\u5408\u6210\u7684\u521b\u65b0\u5de5\u827a\u3002\u8fd9\u79cd\u65b9\u6cd5\u501f\u52a9\u5fae\u751f\u7269\u6216\u690d\u7269\u63d0\u53d6\u7684\u9176\uff0c\u76f4\u63a5\u5c06\u54aa\u5511\u8f6c\u5316\u4e3aN-\u7532\u57fa\u54aa\u5511\u3002\u6574\u4e2a\u8fc7\u7a0b\u65e0\u9700\u4f7f\u7528\u4efb\u4f55\u6709\u6bd2\u8bd5\u5242\uff0c\u771f\u6b63\u5b9e\u73b0\u4e86\u7eff\u8272\u73af\u4fdd\u3002<\/p>\n
\u53cd\u5e94\u673a\u5236<\/h4>\n
\u9176\u4fc3\u53cd\u5e94\u901a\u5e38\u6d89\u53ca\u4ee5\u4e0b\u6b65\u9aa4\uff1a<\/p>\n
\n
\u54aa\u5511\u5206\u5b50\u88ab\u9176\u8bc6\u522b\u5e76\u4e0e\u4e4b\u7ed3\u5408\uff1b <\/li>\n
\u5728\u9176\u7684\u4f5c\u7528\u4e0b\uff0c\u7532\u57fa\u57fa\u56e2\u88ab\u7cbe\u51c6\u8f6c\u79fb\u5230\u54aa\u5511\u73af\u4e0a\uff1b <\/li>\n
\u7ec8\u751f\u6210N-\u7532\u57fa\u54aa\u5511\u5e76\u91ca\u653e\u51fa\u9176\u4f9b\u4e0b\u6b21\u5faa\u73af\u4f7f\u7528\u3002<\/li>\n<\/ol>\n
\u5de5\u827a\u7279\u70b9<\/h3>\n
\n
\n
\u4f18\u70b9<\/strong> <\/p>\n
\n
\u73af\u5883\u53cb\u597d\uff0c\u51e0\u4e4e\u6ca1\u6709\u6c61\u67d3\uff1b <\/li>\n
\u6761\u4ef6\u6e29\u548c\uff0c\u53ef\u5728\u5e38\u6e29\u5e38\u538b\u4e0b\u8fdb\u884c\u3002<\/li>\n<\/ul>\n<\/li>\n
\n
\u7f3a\u70b9<\/strong> <\/p>\n
\n
\u9176\u7684\u6210\u672c\u8f83\u9ad8\uff0c\u9650\u5236\u4e86\u5927\u89c4\u6a21\u5e94\u7528\uff1b <\/li>\n
\u53cd\u5e94\u901f\u5ea6\u8f83\u6162\uff0c\u4ea7\u91cf\u6709\u9650\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n
\u56fd\u5185\u5916\u7814\u7a76\u73b0\u72b6<\/h3>\n
\u7f8e\u56fd\u65af\u5766\u798f\u5927\u5b66\u7684\u4e00\u9879\u7814\u7a76\u8868\u660e\uff0c\u901a\u8fc7\u5bf9\u9176\u7684\u57fa\u56e0\u5e8f\u5217\u8fdb\u884c\u6539\u9020\uff0c\u53ef\u4ee5\u5927\u5e45\u63d0\u5347\u5176\u50ac\u5316\u6548\u7387\u3002\u800c\u5728\u4e2d\u56fd\u519c\u4e1a\u5927\u5b66\uff0c\u7814\u7a76\u4eba\u5458\u5219\u4e13\u6ce8\u4e8e\u7b5b\u9009\u66f4\u9002\u5408\u5de5\u4e1a\u5316\u751f\u4ea7\u7684\u5929\u7136\u9176\u6e90\uff0c\u76ee\u524d\u5df2\u53d6\u5f97\u521d\u6b65\u6210\u679c\u3002<\/p>\n\n\n\n\n\n\n\n
\u53c2\u6570<\/th>\n \u5929\u7136\u9176\u65b9\u6848<\/th>\n \u6539\u9020\u9176\u65b9\u6848<\/th>\n<\/tr>\n<\/thead>\n
\u6d3b\u6027<\/td>\n \u4e2d\u7b49<\/td>\n \u9ad8<\/td>\n<\/tr>\n
\u6210\u672c<\/td>\n \u9ad8<\/td>\n \u8f83\u4f4e<\/td>\n<\/tr>\n
\u9002\u7528\u8303\u56f4<\/td>\n \u5c0f\u89c4\u6a21\u5b9e\u9a8c<\/td>\n \u5927\u89c4\u6a21\u751f\u4ea7<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\n
\u6280\u672f\u521b\u65b0\u4e0e\u6210\u672c\u63a7\u5236<\/h1>\n
\u968f\u7740\u5168\u7403\u5bf9\u7eff\u8272\u5316\u5b66\u7684\u5173\u6ce8\u65e5\u76ca\u589e\u5f3a\uff0c\u5982\u4f55\u5728\u4fdd\u8bc1\u4ea7\u54c1\u8d28\u91cf\u7684\u540c\u65f6\u964d\u4f4e\u751f\u4ea7\u6210\u672c\uff0c\u6210\u4e3aN-\u7532\u57fa\u54aa\u5511\u5408\u6210\u9886\u57df\u7684\u6838\u5fc3\u8bfe\u9898\u3002\u4ee5\u4e0b\u662f\u51e0\u4e2a\u503c\u5f97\u5173\u6ce8\u7684\u6280\u672f\u521b\u65b0\u65b9\u5411\uff1a<\/p>\n
1. \u50ac\u5316\u5242\u5347\u7ea7\u6362\u4ee3<\/h2>\n
\u50ac\u5316\u5242\u7684\u9009\u62e9\u76f4\u63a5\u5f71\u54cd\u7740\u53cd\u5e94\u7684\u6548\u7387\u548c\u7ecf\u6d4e\u6027\u3002\u4f20\u7edf\u7684\u5747\u76f8\u50ac\u5316\u5242\u867d\u7136\u6548\u679c\u663e\u8457\uff0c\u4f46\u56de\u6536\u56f0\u96be\u4e14\u5bb9\u6613\u9020\u6210\u4e8c\u6b21\u6c61\u67d3\u3002\u56e0\u6b64\uff0c\u8fd1\u5e74\u6765\u975e\u5747\u76f8\u50ac\u5316\u5242\u7684\u7814\u53d1\u53d6\u5f97\u4e86\u7a81\u7834\u6027\u8fdb\u5c55\u3002\u4f8b\u5982\uff0c\u8d1f\u8f7d\u578b\u91d1\u5c5e\u50ac\u5316\u5242\u56e0\u5176\u4f18\u5f02\u7684\u7a33\u5b9a\u6027\u548c\u91cd\u590d\u4f7f\u7528\u6027\u80fd\uff0c\u9010\u6e10\u6210\u4e3a\u884c\u4e1a\u65b0\u5ba0\u3002<\/p>\n
2. \u5fae\u53cd\u5e94\u5668\u6280\u672f<\/h2>\n
\u5fae\u53cd\u5e94\u5668\u6280\u672f\u4ee5\u5176\u72ec\u7279\u7684\u4f18\u52bf\u6b63\u5728\u98a0\u8986\u4f20\u7edf\u5316\u5de5\u751f\u4ea7\u6a21\u5f0f\u3002\u901a\u8fc7\u5c06\u53cd\u5e94\u533a\u57df\u7f29\u5c0f\u81f3\u5fae\u7c73\u7ea7\u522b\uff0c\u4e0d\u4ec5\u53ef\u4ee5\u5927\u5e45\u63d0\u9ad8\u4f20\u8d28\u6548\u7387\uff0c\u8fd8\u80fd\u6709\u6548\u907f\u514d\u5c40\u90e8\u8fc7\u70ed\u73b0\u8c61\u7684\u53d1\u751f\u3002\u6b64\u5916\uff0c\u5fae\u53cd\u5e94\u5668\u8fd8\u5177\u5907\u8fde\u7eed\u5316\u64cd\u4f5c\u7684\u80fd\u529b\uff0c\u6709\u52a9\u4e8e\u8fdb\u4e00\u6b65\u538b\u7f29\u751f\u4ea7\u5468\u671f\u3002<\/p>\n
3. \u539f\u6599\u66ff\u4ee3\u7b56\u7565<\/h2>\n
\u5bfb\u627e\u66f4\u52a0\u5ec9\u4ef7\u6613\u5f97\u7684\u539f\u6599\u4e5f\u662f\u964d\u4f4e\u6210\u672c\u7684\u6709\u6548\u624b\u6bb5\u4e4b\u4e00\u3002\u4f8b\u5982\uff0c\u5229\u7528\u519c\u4e1a\u5e9f\u5f03\u7269\u4e2d\u7684\u7ea4\u7ef4\u7d20\u5236\u5907\u4e59\u7094\uff0c\u6216\u8005\u4ece\u7164\u5316\u5de5\u526f\u4ea7\u7269\u4e2d\u63d0\u53d6\u6c28\u6c14\uff0c\u90fd\u662f\u6781\u5177\u6f5c\u529b\u7684\u89e3\u51b3\u65b9\u6848\u3002<\/p>\n
\n
\u7ed3\u8bed\uff1a\u672a\u6765\u7684\u65e0\u9650\u53ef\u80fd<\/h1>\n
\u6b63\u5982\u7231\u56e0\u65af\u5766\u6240\u8a00\uff0c\u201c\u60f3\u8c61\u529b\u6bd4\u77e5\u8bc6\u66f4\u91cd\u8981\u3002\u201d\u5728N-\u7532\u57fa\u54aa\u5511\u7684\u5408\u6210\u9053\u8def\u4e0a\uff0c\u6bcf\u4e00\u6b21\u6280\u672f\u9769\u65b0\u90fd\u51dd\u805a\u7740\u4eba\u7c7b\u667a\u6167\u7684\u7ed3\u6676\u3002\u6211\u4eec\u76f8\u4fe1\uff0c\u968f\u7740\u79d1\u5b66\u6280\u672f\u7684\u4e0d\u65ad\u8fdb\u6b65\uff0c\u672a\u6765\u5fc5\u5c06\u6d8c\u73b0\u51fa\u66f4\u591a\u4ee4\u4eba\u60ca\u53f9\u7684\u521b\u65b0\u6210\u679c\u3002\u800c\u8fd9\uff0c\u6b63\u662f\u5316\u5b66\u7684\u9b45\u529b\u6240\u5728\u2014\u2014\u6c38\u8fdc\u5145\u6ee1\u672a\u77e5\uff0c\u6c38\u8fdc\u503c\u5f97\u671f\u5f85\uff01<\/p>\n
\u53c2\u8003\u6587\u732e\uff1a<\/p>\n
\n
\u5f20\u4f1f\u660e, \u674e\u5f3a. N-\u7532\u57fa\u54aa\u5511\u5408\u6210\u5de5\u827a\u7814\u7a76\u8fdb\u5c55[J]. \u5316\u5de5\u8fdb\u5c55, 2021, 40(1): 12-18.<\/li>\n
Smith J, Brown T. Green Chemistry Approaches for N-Methylimidazole Production[M]. Springer, 2020.<\/li>\n
Wang X, Chen Y. Enzymatic Catalysis in Organic Synthesis: A Review[J]. Journal of Chemical Technology & Biotechnology, 2022, 97(3): 789-801.<\/li>\n
Liu H, Zhao F. Microreactor Technology for Fine Chemicals Synthesis[J]. Chemical Engineering Journal, 2021, 420: 129567.<\/li>\n<\/ol>\n
\u6269\u5c55\u9605\u8bfb:https:\/\/www.bdmaee.net\/dmdee\/<\/a><\/br>
\u6269\u5c55\u9605\u8bfb:https:\/\/www.bdmaee.net\/delayed-amine-catalyst-a-400\/<\/a><\/br>
\u6269\u5c55\u9605\u8bfb:https:\/\/www.bdmaee.net\/lupragen-n109-catalyst-tetramethyldipropylenetriamine-basf\/<\/a><\/br>
\u6269\u5c55\u9605\u8bfb:https:\/\/www.newtopchem.com\/archives\/40045<\/a><\/br>
\u6269\u5c55\u9605\u8bfb:https:\/\/www.newtopchem.com\/archives\/45105<\/a><\/br>
\u6269\u5c55\u9605\u8bfb:https:\/\/www.morpholine.org\/category\/morpholine\/4-formylmorpholine\/<\/a><\/br>
\u6269\u5c55\u9605\u8bfb:https:\/\/www.bdmaee.net\/di-n-octyltin-oxide\/<\/a><\/br>
\u6269\u5c55\u9605\u8bfb:https:\/\/www.newtopchem.com\/archives\/category\/products\/page\/20<\/a><\/br>
\u6269\u5c55\u9605\u8bfb:https:\/\/www.newtopchem.com\/archives\/category\/products\/page\/113<\/a><\/br>
\u6269\u5c55\u9605\u8bfb:https:\/\/www.newtopchem.com\/archives\/category\/products\/page\/124<\/a><\/br><\/p>\n","protected":false},"excerpt":{"rendered":"
N-\u7532\u57fa\u54aa\u5511\uff1a\u4ece\u5b9e\u9a8c\u5ba4\u5230\u5de5\u4e1a\u7684\u5947\u5999\u65c5\u7a0b \u5728\u5316\u5b66\u4e16\u754c\u91cc\uff0c\u6709\u8fd9\u6837\u4e00\u7c7b\u5206\u5b50\uff0c\u5b83\u4eec\u5c31\u50cf\u9690\u85cf\u5728\u89d2\u843d\u91cc\u7684\u9b54\u672f\u5e08\uff0c\u770b\u4f3c\u4e0d\u8d77\u773c\uff0c\u5374\u80fd\u6084\u65e0\u58f0\u606f\u5730\u6539\u53d8\u6211\u4eec\u7684\u751f\u6d3b\u3002N-\u7532\u57fa\u54aa\u5511\uff08N-Methylimidazole, \u7b80\u79f0NMI\uff09\uff0c\u5c31\u662f\u8fd9\u6837\u4e00\u4e2a\u4f4e\u8c03\u5374\u53c8\u4e0d\u53ef\u6216\u7f3a\u7684\u5b58\u5728\u3002\u4f5c\u4e3a\u54aa\u5511\u7c7b\u5316\u5408\u7269\u5bb6\u65cf\u4e2d\u7684\u4e00\u5458\uff0c\u5b83\u4e0d\u4ec5\u62e5\u6709\u8ff7\u4eba\u7684\u5316\u5b66\u7ed3\u6784\uff0c\u8fd8\u5728\u4f17\u591a\u9886\u57df\u5c55\u73b0\u51fa\u975e …<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[4900],"_links":{"self":[{"href":"https:\/\/www.51mdea.com\/wp-json\/wp\/v2\/posts\/5625"}],"collection":[{"href":"https:\/\/www.51mdea.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.51mdea.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.51mdea.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.51mdea.com\/wp-json\/wp\/v2\/comments?post=5625"}],"version-history":[{"count":0,"href":"https:\/\/www.51mdea.com\/wp-json\/wp\/v2\/posts\/5625\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.51mdea.com\/wp-json\/wp\/v2\/media?parent=5625"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.51mdea.com\/wp-json\/wp\/v2\/categories?post=5625"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.51mdea.com\/wp-json\/wp\/v2\/tags?post=5625"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

\u4ec0\u4e48\u662fN-\u7532\u57fa\u54aa\u5511\uff1f<\/h2>\n

\u65b9\u6cd5\u4e00\uff1a\u7532\u57fa\u5316\u6cd5<\/h2>\n

\u53cd\u5e94\u65b9\u7a0b\u5f0f<\/h4>\n$$\ntext{Imidazole} + text{CH}_3text{X} xrightarrow{text{Catalyst}} text{N-Methylimidazole} + text{HX}\n$$<\/p>\n\u5176\u4e2d\uff0c$text{X}$\u4ee3\u8868\u5364\u7d20\u6216\u78fa\u9178\u57fa\u56e2\u3002<\/p>\n

\u65b9\u6cd5\u4e8c\uff1a\u52a0\u6c22\u80fa\u5316\u6cd5<\/h2>\n

\u65b9\u6cd5\u4e09\uff1a\u751f\u7269\u9176\u50ac\u5316\u6cd5<\/h2>\n

\u53cd\u5e94\u65b9\u7a0b\u5f0f<\/h4>\n
$$
\ntext{Imidazole} + text{CH}_3text{X} xrightarrow{text{Catalyst}} text{N-Methylimidazole} + text{HX}
\n$$<\/p>\n
\u5176\u4e2d\uff0c$text{X}$\u4ee3\u8868\u5364\u7d20\u6216\u78fa\u9178\u57fa\u56e2\u3002<\/p>\n